TB-500 | Thymosin Beta-4 Fragment

Research Overview

TB-500 is a synthetic version of a highly conserved region of Thymosin Beta-4 (Tβ4), a naturally occurring peptide present in virtually all human and animal cells.

Research in animal models has investigated TB-500’s interactions with actin — the protein central to cell structure and movement — and its potential roles in tissue repair models, angiogenesis, inflammation modulation, and recovery from injury. Studies have examined its upregulation following tissue damage and its relationship to cell migration and differentiation pathways.

Select Published Research

Goldstein AL et al. (2012). “Thymosin beta4: a multi-functional regenerative peptide.” Expert Opinion on Biological Therapy.
Philp D et al. (2004). “Small peptide induction of collagen IV expression by RPE cells.” Experimental Eye Research.
Crockford D et al. (2010). “Thymosin beta4 and AcSDKP.” Annals of the New York Academy of Sciences.

All referenced studies were conducted in animal or in vitro models. These citations do not constitute claims of human efficacy or safety.

Specifications

Format: Lyophilized powder
Purity: >98% verified by third-party HPLC and mass spectrometry
Storage: Stable at −20°C lyophilized. Reconstituted: refrigerate at 4°C, use within 30 days.
Source: Domestically synthesized

Certificate of Analysis

Third-party COA available in the Lab Results tab above.