NAD+ | Nicotinamide Adenine Dinucleotide

Research Overview

Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme found in all living cells, central to cellular energy metabolism and a substrate for enzymes involved in DNA repair and gene expression regulation.

Research has extensively examined NAD+’s role as a coenzyme in redox reactions, its function as a substrate for sirtuins and poly-ADP ribose polymerases (PARPs), and its decline with age in animal models. Studies have investigated NAD+ precursor supplementation and direct NAD+ administration in the context of cellular energy, mitochondrial function, and neurological models.

Select Published Research

Rajman L et al. (2018). “Therapeutic Potential of NAD-Boosting Molecules.” Cell Metabolism.
Schultz MB & Sinclair DA (2016). “Why NAD+ Declines during Aging.” Cell Metabolism.
Yoshino J et al. (2018). “NAD+ Intermediates.” Cell Metabolism.

All referenced studies were conducted in research settings. These citations do not constitute claims of safety or efficacy for unsupervised use.

Specifications

Format: Lyophilized powder
Purity: >98% verified by HPLC and mass spectrometry
Storage: −20°C lyophilized. Protect from light.
Source: Domestically manufactured

Certificate of Analysis

Third-party COA available in the Lab Results tab above.