{"product_id":"kpv-alpha-msh-c-terminal-tripeptide","title":"KPV | Alpha-MSH C-Terminal Tripeptide","description":"\u003cdiv class=\"ruo-disclaimer\"\u003eFor research use only · Not for human consumption · 18+ required\u003c\/div\u003e\n\n\u003ch2\u003eResearch Overview\u003c\/h2\u003e\n\u003cp\u003eKPV is a C-terminal tripeptide fragment of alpha-melanocyte stimulating hormone (alpha-MSH), specifically the sequence Lysine-Proline-Valine. It acts on melanocortin receptors and has been studied for its anti-inflammatory properties in research models.\u003c\/p\u003e\n\n\u003cp\u003eResearch has investigated KPV’s interactions with MC1R and MC3R receptors, its effects on NF-κB signaling pathways in cell models, and its potential applications in models of inflammatory bowel conditions and skin inflammation in animals. Studies have examined its ability to cross the blood-brain barrier and its central anti-inflammatory effects.\u003c\/p\u003e\n\n\u003ch3\u003eSelect Published Research\u003c\/h3\u003e\n\u003cp\u003eCeriani G et al. (1994). “Central neurogenic anti-inflammatory action of alpha-MSH: modulation of peripheral inflammation.” \u003cem\u003eNeuroendocrinology.\u003c\/em\u003e\u003cbr\u003e\nDalmasso G et al. (2008). “The peptide KPV has anti-inflammatory properties in vitro and in vivo.” \u003cem\u003eInflammatory Bowel Diseases.\u003c\/em\u003e\u003cbr\u003e\nAdan RA et al. (2006). “Melanocortin receptors as drug targets.” \u003cem\u003eDrug Discovery Today.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eAll referenced studies were conducted in animal models or in vitro. These citations do not constitute claims of human efficacy or safety.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilized powder\u003cbr\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;98% verified by HPLC and mass spectrometry\u003cbr\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e −20°C lyophilized. Reconstituted: 4°C, use within 30 days.\u003cbr\u003e\n\u003cstrong\u003eSource:\u003c\/strong\u003e Domestically synthesized\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch2\u003eCertificate of Analysis\u003c\/h2\u003e\n\u003cp\u003eThird-party COA available in the \u003cstrong\u003eLab Results\u003c\/strong\u003e tab above.\u003c\/p\u003e\n\n\u003cdiv class=\"ruo-disclaimer\"\u003eFor research use only. Not for human consumption. Must be 18+ to purchase.\u003c\/div\u003e","brand":"Ripple Health","offers":[{"title":"Default Title","offer_id":46053640372412,"sku":null,"price":0.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0761\/0485\/9836\/files\/kpv.png?v=1773434710","url":"https:\/\/www.myripplehealth.com\/products\/kpv-alpha-msh-c-terminal-tripeptide","provider":"Ripple Health","version":"1.0","type":"link"}